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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1B
All Species:
19.7
Human Site:
S745
Identified Species:
43.33
UniProt:
Q00975
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00975
NP_000709.1
2339
262496
S745
A
K
E
V
A
E
V
S
P
M
S
A
A
N
I
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S1194
A
K
E
V
A
E
V
S
P
M
S
A
A
N
I
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S736
L
Q
K
A
K
E
V
S
P
M
S
A
P
N
M
Dog
Lupus familis
XP_537779
2046
229120
S569
V
M
Y
H
G
I
E
S
Q
G
G
V
S
K
G
Cat
Felis silvestris
Mouse
Mus musculus
O55017
2327
261463
S745
A
K
E
V
A
E
V
S
P
M
S
A
A
N
I
Rat
Rattus norvegicus
Q02294
2336
262238
S746
A
K
E
V
A
E
V
S
P
M
S
A
A
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
E622
V
V
C
G
G
I
V
E
T
I
L
V
E
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
G352
A
G
R
N
P
N
Y
G
Y
T
S
Y
D
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
A373
E
K
M
H
I
M
E
A
R
R
R
N
A
A
K
Honey Bee
Apis mellifera
NP_001159376
1904
215872
L427
N
W
I
Y
F
I
P
L
I
V
L
G
S
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
S489
K
E
E
S
F
G
L
S
V
L
R
A
L
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
54.2
80.1
N.A.
91.9
92.1
N.A.
N.A.
38.3
N.A.
20.7
N.A.
44.7
47.6
N.A.
39.5
Protein Similarity:
100
82.3
65.5
82.2
N.A.
94.4
94.5
N.A.
N.A.
53.3
N.A.
36
N.A.
56
58.7
N.A.
52.4
P-Site Identity:
100
100
53.3
6.6
N.A.
100
100
N.A.
N.A.
6.6
N.A.
20
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
100
73.3
13.3
N.A.
100
100
N.A.
N.A.
13.3
N.A.
20
N.A.
20
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
10
37
0
0
10
0
0
0
55
46
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
10
46
0
0
46
19
10
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
19
0
0
0
0
0
0
0
0
10
19
% F
% Gly:
0
10
0
10
19
10
0
10
0
10
10
10
0
0
10
% G
% His:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
28
0
0
10
10
0
0
0
0
37
% I
% Lys:
10
46
10
0
10
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
10
0
0
0
0
0
10
10
0
10
19
0
10
10
10
% L
% Met:
0
10
10
0
0
10
0
0
0
46
0
0
0
0
10
% M
% Asn:
10
0
0
10
0
10
0
0
0
0
0
10
0
55
0
% N
% Pro:
0
0
0
0
10
0
10
0
46
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
10
10
19
0
0
10
0
% R
% Ser:
0
0
0
10
0
0
0
64
0
0
55
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% T
% Val:
19
10
0
37
0
0
55
0
10
10
0
19
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
10
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _